Simpler-looking trial architectures often sit in the quietest registry segments

Dashboard

Open dashboard at root Read E156 micro-paper Open protocol Open series hub

Arm counts and intervention counts expose a structural quiet zone that would be invisible in a sponsor-only reading.

How to read the dashboard

1-arm no results

72.8%

Smallest architecture

10+ arms no results

55.3%

Largest architecture

1-intervention ghosts

47.5%

Single intervention

PHASE1 one-arm

88.5%

Within-phase architecture

Arm-group architecture

One-arm studies are not the clean edge case of the registry. They are one of its quietest structural segments.

The architecture page starts with arm count because it is the clearest public marker of protocol simplicity.

Intervention count

Single-intervention studies are also much quieter than more complex intervention structures.

The intervention count chart keeps the architecture story from depending on arm groups alone.

Within-phase architecture

The architecture gap remains visible inside both early and later phases rather than collapsing into pure phase mix.

That makes the architecture signal a real structural layer in the registry rather than just a side effect of phase.

Read Across Projects

Across The Series

Each project isolates a different dimension of registry opacity, but the point is the contrast between them, not a single leaderboard.

Industry

CT.gov Industry Disclosure Gap

Industry-focused missing-results stock, sponsor backlogs, and structural sparsity inside CT.gov.

Sponsor Classes

CT.gov Sponsor-Class Hiddenness

Sponsor-class comparisons on rate, stock, and structural hiddenness rather than one flattened ranking.

Phases

CT.gov Phase Reporting Gap

Phase-by-phase disclosure gaps showing how silence changes along the development pathway.

Structural

CT.gov Structural Missingness

Field-level missingness across publication links, IPD statements, descriptions, and locations.

Visibility

CT.gov Evidence Visibility Gap

Results-plus-publication visibility states showing how many older trials are fully visible, partly visible, or ghosted.

Cohorts

CT.gov Completion Cohort Debt

Completion-era reporting debt showing how older eligible cohorts drift on no-results and ghost-protocol rates.

Conditions

CT.gov Condition Hiddenness Map

Keyword-classified therapeutic-area hiddenness mapping across common condition families.

Concentration

CT.gov Sponsor Backlog Concentration

Concentration and inequality analysis showing how much unresolved stock sits inside a thin sponsor slice.

Rule Eras

CT.gov Rule-Era Reporting Gap

Policy-era comparisons across pre-FDAAA, FDAAA, and later CT.gov completion cohorts.

PubMed Audit

CT.gov Publication Undercount Audit

Sample-based external PubMed NCT audit testing how often CT.gov no-link records hide an external paper trail.

Oncology

CT.gov Oncology Hiddenness

Oncology-specific CT.gov hiddenness showing where cancer-trial stock, phases, and sponsors still go quiet.

Cardiovascular

CT.gov Cardiovascular Hiddenness

Cardiovascular CT.gov hiddenness showing how heart and vascular studies remain quiet across major phases and sponsors.

Metabolic

CT.gov Metabolic Hiddenness

Metabolic CT.gov hiddenness across obesity, diabetes, and related trial portfolios with large late-phase and NA stock.

Size

CT.gov Enrollment-Size Gap

Enrollment-size gradients showing how older small trials remain much quieter than larger registered studies.

Geography

CT.gov Geography-Scale Visibility

Site and country footprint analysis showing how larger trial geographies map onto much better public visibility.

Purpose

CT.gov Design-Purpose Hiddenness

Primary-purpose and allocation analysis showing which trial intents remain most obscured on CT.gov.

Delay

CT.gov Completion-Delay Debt

Registration-to-completion delay analysis showing short-cycle studies carry the heaviest reporting debt.