CT.gov Condition Primary-Only Gap
2026-03-29 | full-registry ct.gov audit | plots, figures, and e156 bundle
Series
IndustrySponsor-ClassPhaseStructural MissingnessEvidence VisibilityCompletion CohortCondition HiddennessSponsor ConcentrationRule-Era ReportingPublication UndercountOncology HiddennessCardiovascular HiddennessMetabolic HiddennessEnrollment-SizeGeography-ScaleDesign-PurposeCompletion-DelayTrial-ArchitectureIntervention-TypeCountry ReportingStopped-TrialOutcome-DensityActual-FieldUs-Versus-GlobalModality-SponsorCountry-ConditionDisease-GeographyCondition-SponsorCountry-SponsorUs-Versus-Ex-UsIndustry-FamilyRisk-Adjusted HiddennessOverdue Results ClockPublication Index GapProbable Act/Fdaaa DebtSponsor Excess WatchlistCountry Excess WatchlistCondition Excess WatchlistBlack-Box TrialsStrict-Proxy RepeatersSponsor Ghost RepeatersCountry Ghost WatchlistCondition Ghost WatchlistBlack-Box Sponsor RepeatersStrict-Core Black-BoxSponsor Overdue DebtCountry Overdue DebtCondition Overdue DebtNarrative-Gap RepeatersActual-Discipline RepeatersSponsor Ancient BacklogCountry Ancient BacklogCondition Ancient BacklogDescription-Black-Box RepeatersCompletion-Timing RepeatersCountry Description Black-BoxCondition Description Black-BoxSponsor Enrollment-Gap RepeatersCountry Enrollment-GapCondition Enrollment-GapCountry Narrative-GapCondition Narrative-GapSponsor Primary-Outcome-GapCountry Primary-Outcome-GapCondition Primary-Outcome-GapSponsor Detailed-Description-GapCountry Detailed-Description-GapCondition Detailed-Description-GapSponsor Text AsymmetryCountry Text AsymmetrySponsor Primary-OnlyCountry Primary-OnlyCondition Primary-OnlyCondition AsymmetryClass Primary-Only
E156 Micro-Paper

CT.gov Condition Primary-Only Gap

A 156-word micro-paper on which therapeutic CT.gov portfolios most often omit endpoint text while the broad study narrative remains.

Oncology
Other
Cardiovascular
Infectious disease

Paper

Oncology dominates the primary-only map on both stock and rate, making endpoint-only text loss a central oncology registry problem rather than a fringe issue.

Reading note

Which condition families most often leave older CT.gov study pages without the primary outcome description while keeping the broader detailed-description field? We analysed 249,507 eligible older closed interventional studies from the March 29, 2026 full-registry snapshot using one condition-family label per study. We defined a primary-only gap as missing primary outcome description with detailed description still present, then ranked large condition families by stock and rate. Oncology led the condition-family primary-only-gap stock table at 7,102 studies, followed by Other at 5,818, Cardiovascular at 3,766, and Infectious disease at 2,584. Oncology also had the highest large-family primary-only-gap rate at 16.8 percent, ahead of Cardiovascular at 14.5 percent and Infectious disease at 14.3 percent. Condition-family primary-only gaps show where the endpoint sentence disappears most often even though the broader study narrative remains on the page. Condition families are keyword-derived registry groupings rather than formal disease ontologies or mutually exclusive diagnoses across all studies. They simplify diagnoses for readers.

Oncology gap
7,102
Primary-only gaps
Other gap
5,818
Primary-only gaps
Cardio gap
3,766
Primary-only gaps
Infectious gap
2,584
Primary-only gaps