CT.gov Condition Primary-Only Gap
2026-03-29 | full-registry ct.gov audit | plots, figures, and e156 bundle
Series
IndustrySponsor-ClassPhaseStructural MissingnessEvidence VisibilityCompletion CohortCondition HiddennessSponsor ConcentrationRule-Era ReportingPublication UndercountOncology HiddennessCardiovascular HiddennessMetabolic HiddennessEnrollment-SizeGeography-ScaleDesign-PurposeCompletion-DelayTrial-ArchitectureIntervention-TypeCountry ReportingStopped-TrialOutcome-DensityActual-FieldUs-Versus-GlobalModality-SponsorCountry-ConditionDisease-GeographyCondition-SponsorCountry-SponsorUs-Versus-Ex-UsIndustry-FamilyRisk-Adjusted HiddennessOverdue Results ClockPublication Index GapProbable Act/Fdaaa DebtSponsor Excess WatchlistCountry Excess WatchlistCondition Excess WatchlistBlack-Box TrialsStrict-Proxy RepeatersSponsor Ghost RepeatersCountry Ghost WatchlistCondition Ghost WatchlistBlack-Box Sponsor RepeatersStrict-Core Black-BoxSponsor Overdue DebtCountry Overdue DebtCondition Overdue DebtNarrative-Gap RepeatersActual-Discipline RepeatersSponsor Ancient BacklogCountry Ancient BacklogCondition Ancient BacklogDescription-Black-Box RepeatersCompletion-Timing RepeatersCountry Description Black-BoxCondition Description Black-BoxSponsor Enrollment-Gap RepeatersCountry Enrollment-GapCondition Enrollment-GapCountry Narrative-GapCondition Narrative-GapSponsor Primary-Outcome-GapCountry Primary-Outcome-GapCondition Primary-Outcome-GapSponsor Detailed-Description-GapCountry Detailed-Description-GapCondition Detailed-Description-GapSponsor Text AsymmetryCountry Text AsymmetrySponsor Primary-OnlyCountry Primary-OnlyCondition Primary-OnlyCondition AsymmetryClass Primary-Only
Condition Primary-Only-Gap Dashboard

Condition primary-only-gap tables show where endpoint text disappears while the broad study narrative survives

Oncology dominates condition-family primary-only-gap stock and rate, while Cardiovascular, Infectious disease, and Metabolic remain large on count and Renal portfolios stay elevated on rate.

Open dashboardRead E156 paperProtocolSeries hub
Primary-only stock
Rate
Conditions
Endpoints

Dashboard

Open dashboard at rootRead E156 micro-paperOpen protocolOpen series hub

Oncology leads condition-family primary-only-gap stock and also leads on rate, while Cardiovascular and Infectious disease remain substantial on count.

How to read the dashboard
Oncology gap
7,102
Primary-only gaps
Other gap
5,818
Primary-only gaps
Oncology rate
16.8%
Large-family rate
Cardio rate
14.4%
Large-family rate
Primary-only-gap stock
PRIMARY-ONLY STOCKTop condition-family counts missing endpoint text while narrative remainsOncology7,102Other5,818Cardiovascular3,766Infectious disease2,584Metabolic2,444Mental health2,014Healthy volunteers1,848Musculoskeletal and pain1,687Respiratory and sleep1,180Neurology1,035
Oncology dominates on count, with Other and Cardiovascular also carrying large endpoint-only portfolios.
This field gap therefore sits in major therapeutic areas, not only small fringe categories.
Primary-only-gap rate
PRIMARY-ONLY RATELarge-family primary-only-gap rateOncology16.8%Cardiovascular14.4%Infectious disease14.3%Renal and urology14.2%Metabolic14.1%Reproductive and maternal13.9%Healthy volunteers13.1%Gastrointestinal and hepatic13.1%Respiratory and sleep13.0%Mental health10.9%
Oncology is the sharpest large-family rate outlier, with Cardiovascular and Infectious disease just behind.
Rate confirms the endpoint-only problem is concentrated in major disease areas.
Description-only stock
DESCRIPTION-ONLY STOCKBroad narrative gaps while endpoint text remainsOther13,517Oncology8,216Cardiovascular5,568Musculoskeletal and pain4,208Infectious disease4,049Healthy volunteers3,982Metabolic3,887Mental health3,803Neurology2,555Respiratory and sleep2,358
Description-only stock remains even larger in several therapeutic portfolios than primary-only stock.
That broader text imbalance is why the companion condition asymmetry project matters.
Read Across Projects

Across The Series

Each project isolates a different dimension of registry opacity, but the point is the contrast between them, not a single leaderboard.

Industry
Industry project

Industry project from the CT.gov hiddenness series.

Sponsor-Class
Sponsor-class project

Sponsor-class project from the CT.gov hiddenness series.

Phase
Phase project

Phase project from the CT.gov hiddenness series.

Structural Missingness
Structural missingness project

Structural missingness project from the CT.gov hiddenness series.

Evidence Visibility
Evidence visibility project

Evidence visibility project from the CT.gov hiddenness series.

Completion Cohort
Completion cohort project

Completion cohort project from the CT.gov hiddenness series.

Condition Hiddenness
Condition hiddenness project

Condition hiddenness project from the CT.gov hiddenness series.

Sponsor Concentration
Sponsor concentration project

Sponsor concentration project from the CT.gov hiddenness series.

Rule-Era Reporting
Rule-era reporting project

Rule-era reporting project from the CT.gov hiddenness series.

Publication Undercount
Publication undercount audit

Publication undercount audit from the CT.gov hiddenness series.

Oncology Hiddenness
Oncology hiddenness project

Oncology hiddenness project from the CT.gov hiddenness series.

Cardiovascular Hiddenness
Cardiovascular hiddenness project

Cardiovascular hiddenness project from the CT.gov hiddenness series.

Metabolic Hiddenness
Metabolic hiddenness project

Metabolic hiddenness project from the CT.gov hiddenness series.

Enrollment-Size
Enrollment-size project

Enrollment-size project from the CT.gov hiddenness series.

Geography-Scale
Geography-scale project

Geography-scale project from the CT.gov hiddenness series.

Design-Purpose
Design-purpose project

Design-purpose project from the CT.gov hiddenness series.

Completion-Delay
Completion-delay project

Completion-delay project from the CT.gov hiddenness series.

Trial-Architecture
Trial-architecture project

Trial-architecture project from the CT.gov hiddenness series.

Intervention-Type
Intervention-type project

Intervention-type project from the CT.gov hiddenness series.

Country Reporting
Country reporting project

Country reporting project from the CT.gov hiddenness series.

Stopped-Trial
Stopped-trial project

Stopped-trial project from the CT.gov hiddenness series.

Outcome-Density
Outcome-density project

Outcome-density project from the CT.gov hiddenness series.

Actual-Field
Actual-field project

Actual-field project from the CT.gov hiddenness series.

Us-Versus-Global
US-versus-global project

US-versus-global project from the CT.gov hiddenness series.

Modality-Sponsor
Modality-sponsor project

Modality-sponsor project from the CT.gov hiddenness series.

Country-Condition
Country-condition project

Country-condition project from the CT.gov hiddenness series.

Disease-Geography
Disease-geography project

Disease-geography project from the CT.gov hiddenness series.

Condition-Sponsor
Condition-sponsor project

Condition-sponsor project from the CT.gov hiddenness series.

Country-Sponsor
Country-sponsor project

Country-sponsor project from the CT.gov hiddenness series.

Us-Versus-Ex-Us
US-versus-ex-US project

US-versus-ex-US project from the CT.gov hiddenness series.

Industry-Family
Industry-family project

Industry-family project from the CT.gov hiddenness series.

Risk-Adjusted Hiddenness
Risk-adjusted hiddenness

Risk-adjusted hiddenness from the CT.gov hiddenness series.

Overdue Results Clock
Overdue results clock

Overdue results clock from the CT.gov hiddenness series.

Publication Index Gap
Publication index gap

Publication index gap from the CT.gov hiddenness series.

Probable Act/Fdaaa Debt
Probable ACT/FDAAA debt

Probable ACT/FDAAA debt from the CT.gov hiddenness series.

Sponsor Excess Watchlist
Sponsor excess watchlist

Sponsor excess watchlist from the CT.gov hiddenness series.

Country Excess Watchlist
Country excess watchlist

Country excess watchlist from the CT.gov hiddenness series.

Condition Excess Watchlist
Condition excess watchlist

Condition excess watchlist from the CT.gov hiddenness series.

Black-Box Trials
Black-box trials

Black-box trials from the CT.gov hiddenness series.

Strict-Proxy Repeaters
Strict-proxy repeaters

Strict-proxy repeaters from the CT.gov hiddenness series.

Sponsor Ghost Repeaters
Sponsor ghost repeaters

Sponsor ghost repeaters from the CT.gov hiddenness series.

Country Ghost Watchlist
Country ghost watchlist

Country ghost watchlist from the CT.gov hiddenness series.

Condition Ghost Watchlist
Condition ghost watchlist

Condition ghost watchlist from the CT.gov hiddenness series.

Black-Box Sponsor Repeaters
Black-box sponsor repeaters

Black-box sponsor repeaters from the CT.gov hiddenness series.

Strict-Core Black-Box
Strict-core black-box

Strict-core black-box from the CT.gov hiddenness series.

Sponsor Overdue Debt
Sponsor overdue debt

Sponsor overdue debt from the CT.gov hiddenness series.

Country Overdue Debt
Country overdue debt

Country overdue debt from the CT.gov hiddenness series.

Condition Overdue Debt
Condition overdue debt

Condition overdue debt from the CT.gov hiddenness series.

Narrative-Gap Repeaters
Narrative-gap repeaters

Narrative-gap repeaters from the CT.gov hiddenness series.

Actual-Discipline Repeaters
Actual-discipline repeaters

Actual-discipline repeaters from the CT.gov hiddenness series.

Sponsor Ancient Backlog
Sponsor ancient backlog

Sponsor ancient backlog from the CT.gov hiddenness series.

Country Ancient Backlog
Country ancient backlog

Country ancient backlog from the CT.gov hiddenness series.

Condition Ancient Backlog
Condition ancient backlog

Condition ancient backlog from the CT.gov hiddenness series.

Description-Black-Box Repeaters
Description-black-box repeaters

Description-black-box repeaters from the CT.gov hiddenness series.

Completion-Timing Repeaters
Completion-timing repeaters

Completion-timing repeaters from the CT.gov hiddenness series.

Country Description Black-Box
Country description black-box

Country description black-box from the CT.gov hiddenness series.

Condition Description Black-Box
Condition description black-box

Condition description black-box from the CT.gov hiddenness series.

Sponsor Enrollment-Gap Repeaters
Sponsor enrollment-gap repeaters

Sponsor enrollment-gap repeaters from the CT.gov hiddenness series.

Country Enrollment-Gap
Country enrollment-gap

Country enrollment-gap from the CT.gov hiddenness series.

Condition Enrollment-Gap
Condition enrollment-gap

Condition enrollment-gap from the CT.gov hiddenness series.

Country Narrative-Gap
Country narrative-gap

Country narrative-gap from the CT.gov hiddenness series.

Condition Narrative-Gap
Condition narrative-gap

Condition narrative-gap from the CT.gov hiddenness series.

Sponsor Primary-Outcome-Gap
Sponsor primary-outcome-gap

Sponsor primary-outcome-gap from the CT.gov hiddenness series.

Country Primary-Outcome-Gap
Country primary-outcome-gap

Country primary-outcome-gap from the CT.gov hiddenness series.

Condition Primary-Outcome-Gap
Condition primary-outcome-gap

Condition primary-outcome-gap from the CT.gov hiddenness series.

Sponsor Detailed-Description-Gap
Sponsor detailed-description-gap

Sponsor detailed-description-gap from the CT.gov hiddenness series.

Country Detailed-Description-Gap
Country detailed-description-gap

Country detailed-description-gap from the CT.gov hiddenness series.

Condition Detailed-Description-Gap
Condition detailed-description-gap

Condition detailed-description-gap from the CT.gov hiddenness series.

Sponsor Text Asymmetry
Sponsor text asymmetry

Sponsor text asymmetry from the CT.gov hiddenness series.

Country Text Asymmetry
Country text asymmetry

Country text asymmetry from the CT.gov hiddenness series.

Sponsor Primary-Only
CT.gov Sponsor Primary-Only Gap

Named-sponsor tables showing where endpoint text disappears while the broad study narrative remains.

Country Primary-Only
CT.gov Country Primary-Only Gap

Country-linked tables showing where endpoint text disappears while the broad study narrative remains.

Condition Asymmetry
CT.gov Condition Text Asymmetry

Condition-family tables showing where broad study narratives disappear much more often than endpoint-only text.

Class Primary-Only
CT.gov Sponsor-Class Primary-Only Gap

Sponsor-class tables showing where endpoint text disappears while the broad study narrative remains.

Source on GitHub | Project home | Dashboard