Research Tool Only: This application is intended for research and educational purposes. It does not constitute medical advice, diagnosis, or treatment recommendations. Clinical decisions must be made by qualified healthcare professionals using complete patient information. Guideline recommendations shown are summaries and may not reflect the full context, caveats, or patient-specific considerations of the source documents.

MetaSprint DTA Cardio Diagnostics

Day 1/40

MetaSprint DTA — Diagnostic Test Accuracy Meta-Analysis

Project Health
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40
Days Left
34
Days to Freeze
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Gates Passed
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Studies
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Day 3: ProtocolDay 10: SearchDay 28: ExtractDay 33: AnalysisDay 40: Submit
Project Risk
LOW
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Your Tasks Today
40-Day Timeline
40-Day sprint timeline phases and gates
PhaseDaysGateStatus

Definition of Done (DoD) Checkpoints

Track completion of each quality gate. All items must be checked before a gate can be signed off.

Discover — Evidence Landscape

Scoping phase (PRISMA-DTA): Explore the cardiovascular DTA landscape to identify gaps and formulate your review question. Define your PIRD in the Protocol tab before proceeding to formal Search. Discovery findings should inform — not determine — your research question.
Search for diagnostic accuracy studies across open registries. Sensitivity/specificity are back-calculated into 2×2 tables and imported into your extraction sheet. Scoping tool only — results are extracted from abstracts and registry records (no full-text), covering CT.gov, Europe PMC, and OpenAlex. This does not replace systematic search (Embase, CINAHL, etc.) or full-text data extraction for formal reviews.
70 validated topics across 11 specialties
Pick a subspecialty for fast loading (~10-30 sec)

PROSPERO Protocol (DTA)

Define your review question using PIRD (Population, Index test, Reference standard, Diagnosis/target condition). The generated protocol can be submitted to PROSPERO.

Abstract Screening

0 references

Select a reference to view details

PRISMA Flow

Quick Start: Enter TP/FP/FN/TN for each study below, or Load Demo Data. Then switch to the Analyze tab.

DTA Data Extraction

Enter counts from each study's 2×2 table: TP (true positives: disease present, test positive), FP (false positives: disease absent, test positive), FN (false negatives: disease present, test negative), TN (true negatives: disease absent, test negative). Zero-cell studies get continuity correction (default +0.5).
DTA data extraction table — 2x2 diagnostic accuracy counts
Author/Year *PMIDDOI Index TestThresholdRef StandardPopulation TP * FP * FN * TN * Sens Spec Covariate Subgroup Notes

Quality Assessment (QUADAS-2) ▼

DTA Analysis Dashboard

Bivariate: default for most DTA reviews. HSROC: preferred when threshold effect is significant.

Sensitivity

Specificity

Coupled Forest Plot

Paper Generator

Auto-generate Methods and Results sections from your review data.

Evidence Insights

Deep evidence analysis inspired by Quranic epistemological principles. Select a sub-tab to explore.

Tawakkul — Trust Decomposition

8-axis radar showing trustworthiness dimensions of the current evidence base. Each axis maps to a GRADE or methodological quality domain.

Mizan — Harm-Benefit Equipoise

Balance-scale visualization weighing benefits against harms for the pooled intervention.

Shura — Multiverse Specification Curve

How sensitive are results to analytic choices? Runs all permutations of model, estimator, and adjustments.

Hikmah — Clinical Decision Context

NND, PPV/NPV calculator. Adjust disease prevalence to see how diagnostic test accuracy translates to clinical predictions.

Fitrah — Natural Query Interface

Ask questions about your evidence in plain language.

Ihsan — Excellence in Uncertainty Communication

Quantile dot plots and icon arrays that convey uncertainty more intuitively than confidence intervals alone.

Amanah — Evidence Gap Accountability

Structured registry of what evidence is missing. Gaps scored by disease burden, feasibility, and equity impact.

Taqwa — Integrity Sentinel

Automated checks for DTA data integrity: 2x2 cell consistency, sensitivity/specificity plausibility, sample size adequacy, and funding bias indicators.

Dhulm — Health Equity Detector

Assesses whether the evidence base represents the populations who bear the disease burden.

Rahma — Patient-Facing Translation

Generates plain-language summaries at 8th-grade reading level. Designed for shared decision-making.

Tabayyun — Verification Engine

Quran 49:6: "Verify before acting." Every evidence claim gets a cross-source verification state. No insight is trusted unless corroborated by 2+ independent sources.

Living Evidence Mode

PRISMA-LSR compliant currency tracking. Shows when evidence was last verified, what changed, and what needs updating.

Conflict Detector

Identifies contradictory outcomes across different sources, study updates, or time periods within the evidence base.

Opportunity Radar — New Since Last MA

Identifies test-condition pairs where new trials have emerged since the last published meta-analysis, creating opportunities for updated reviews.

Registry Graph — Canonical Record Linking

Links NCT IDs, PMIDs, and DOIs into unified canonical records. Detects duplicate registrations and publication-registration mismatches.