Mahmood Ahmad
Tahir Heart Institute
author@example.com

Protocol: CT.gov Sponsor Text Asymmetry

This protocol isolates description-vs-endpoint text imbalance inside named-sponsor CT.gov portfolios. A description-only gap is a study missing the detailed description field while retaining the primary outcome description, and a primary-only gap is the reverse. Net text asymmetry is description-only minus primary-only counts and rates. Primary outputs rank named sponsors with at least 100 studies by net asymmetry and asymmetry rate.

Outside Notes

Type: protocol
Primary estimand: Net description-vs-endpoint asymmetry among older studies, defined as description-only gaps minus primary-only gaps
App: CT.gov Sponsor Text Asymmetry dashboard
Code: https://github.com/mahmood726-cyber/ctgov-sponsor-text-asymmetry
Date: 2026-03-29
Validation: FULL REGISTRY RUN

References

1. ClinicalTrials.gov API v2. National Library of Medicine. Accessed March 29, 2026.
2. DeVito NJ, Bacon S, Goldacre B. Compliance with legal requirement to report clinical trial results on ClinicalTrials.gov: a cohort study. Lancet. 2020;395(10221):361-369.
3. Zarin DA, Tse T, Williams RJ, Carr S. Trial reporting in ClinicalTrials.gov. N Engl J Med. 2016;375(20):1998-2004.

AI Disclosure

This work represents a compiler-generated evidence micro-publication built from structured registry data and deterministic summary code. AI was used as a constrained coding and drafting assistant for interface generation, packaging, and prose refinement, not as an autonomous author. The analytical choices, interpretation, and final outputs were reviewed by the author, who takes responsibility for the content.