Mahmood Ahmad
Tahir Heart Institute
author@example.com

Protocol: CT.gov Outcome-Density Gap

This protocol groups eligible older closed interventional ClinicalTrials.gov studies by primary outcome count, secondary outcome count, and primary-outcome description presence. Primary outputs compare two-year no-results rates, ghost-protocol rates, and fully visible shares across sparse and dense outcome structures, with a secondary description-field contrast. The aim is to test whether sparser declared outcome structure corresponds to a visibly thinner public record. Because outcome counts are registry structure fields, the project measures declared protocol density rather than endpoint quality or scientific importance.

Outside Notes

Type: protocol
Primary estimand: 2-year no-results rate across outcome-density buckets among eligible older CT.gov studies
App: CT.gov Outcome-Density Gap dashboard
Code: https://github.com/mahmood726-cyber/ctgov-outcome-density-gap
Date: 2026-03-29
Validation: FULL REGISTRY RUN

References

1. ClinicalTrials.gov API v2. National Library of Medicine. Accessed March 29, 2026.
2. Zarin DA, Tse T, Williams RJ, Carr S. Trial reporting in ClinicalTrials.gov. N Engl J Med. 2016;375(20):1998-2004.
3. DeVito NJ, Bacon S, Goldacre B. Compliance with legal requirement to report clinical trial results on ClinicalTrials.gov: a cohort study. Lancet. 2020;395(10221):361-369.

AI Disclosure

This work represents a compiler-generated evidence micro-publication built from structured registry data and deterministic summary code. AI was used as a constrained coding and drafting assistant for interface generation, packaging, and prose refinement, not as an autonomous author. The analytical choices, interpretation, and final outputs were reviewed by the author, who takes responsibility for the content.