Mahmood Ahmad
Tahir Heart Institute
author@example.com

Protocol: CT.gov Modality Sponsor Repeaters

This protocol groups eligible older closed interventional ClinicalTrials.gov studies by declared intervention family and then ranks lead sponsors within each modality. Primary outputs compare sponsor-level missing-results counts, no-results rates, ghost-protocol rates, and fully visible shares within drug, device, procedure, behavioral, biological, and dietary-supplement families. The aim is to test whether repeat offenders are stable across intervention types or whether modality-specific sponsor clusters are being hidden inside whole-registry tables. Because both sponsor and intervention labels are registry-entered, the analysis measures declared modality and lead-sponsor naming rather than corporate ownership or collaboration depth.

Outside Notes

Type: protocol
Primary estimand: Sponsor-level 2-year no-results counts within intervention families among eligible older CT.gov studies
App: CT.gov Modality Sponsor Repeaters dashboard
Code: https://github.com/mahmood726-cyber/ctgov-modality-sponsor-repeaters
Date: 2026-03-29
Validation: FULL REGISTRY RUN

References

1. ClinicalTrials.gov API v2. National Library of Medicine. Accessed March 29, 2026.
2. Zarin DA, Tse T, Williams RJ, Carr S. Trial reporting in ClinicalTrials.gov. N Engl J Med. 2016;375(20):1998-2004.
3. DeVito NJ, Bacon S, Goldacre B. Compliance with legal requirement to report clinical trial results on ClinicalTrials.gov: a cohort study. Lancet. 2020;395(10221):361-369.

AI Disclosure

This work represents a compiler-generated evidence micro-publication built from structured registry data and deterministic summary code. AI was used as a constrained coding and drafting assistant for interface generation, packaging, and prose refinement, not as an autonomous author. The analytical choices, interpretation, and final outputs were reviewed by the author, who takes responsibility for the content.