Mahmood Ahmad
Tahir Heart Institute
author@example.com

Protocol: CT.gov Industry Family Repeaters

This protocol isolates industry-sponsored eligible older closed interventional ClinicalTrials.gov studies, explodes intervention families, and ranks sponsors within each family. Primary outputs compare sponsor-level missing-results counts, no-results rates, ghost-protocol rates, and fully visible shares across drug, device, procedure, biological, and dietary-supplement families, with a secondary geography contrast for industry portfolios. The aim is to test whether the pooled industry backlog hides distinct family-specific repeater structures and cross-border visibility gradients. Because sponsor, intervention, and country fields are registry-entered, the analysis measures registry-visible industry structure rather than audited corporate, therapeutic, or legal classifications.

Outside Notes

Type: protocol
Primary estimand: Industry sponsor missing-results counts within intervention families among eligible older CT.gov studies
App: CT.gov Industry Family Repeaters dashboard
Code: https://github.com/mahmood726-cyber/ctgov-industry-family-repeaters
Date: 2026-03-29
Validation: FULL REGISTRY RUN

References

1. ClinicalTrials.gov API v2. National Library of Medicine. Accessed March 29, 2026.
2. Zarin DA, Tse T, Williams RJ, Carr S. Trial reporting in ClinicalTrials.gov. N Engl J Med. 2016;375(20):1998-2004.
3. DeVito NJ, Bacon S, Goldacre B. Compliance with legal requirement to report clinical trial results on ClinicalTrials.gov: a cohort study. Lancet. 2020;395(10221):361-369.

AI Disclosure

This work represents a compiler-generated evidence micro-publication built from structured registry data and deterministic summary code. AI was used as a constrained coding and drafting assistant for interface generation, packaging, and prose refinement, not as an autonomous author. The analytical choices, interpretation, and final outputs were reviewed by the author, who takes responsibility for the content.
