Mahmood Ahmad
Tahir Heart Institute
author@example.com

Protocol: CT.gov Industry Disclosure Gap

This protocol isolates the industry-linked segment of the March 29, 2026 ClinicalTrials.gov full-registry snapshot. The source universe includes 128,464 industry-linked studies, including 87,296 closed interventional industry studies. The primary estimand is the 2-year no-results rate among eligible older closed interventional industry studies, with secondary estimates for missing actual dates, missing actual enrollment, absent IPD statements, absent linked publication references, and absent detailed descriptions. Outputs emphasize both absolute sponsor backlogs and rate-based sponsor silence so large multinational portfolios are not conflated with smaller sponsors showing near-complete non-reporting.

Outside Notes

Type: protocol
Primary estimand: 2-year no-results rate among eligible older closed interventional industry studies
App: CT.gov Industry Disclosure Gap dashboard
Code: https://github.com/mahmood726-cyber/ctgov-industry-disclosure-gap
Date: 2026-03-29
Validation: FULL REGISTRY RUN

References

1. ClinicalTrials.gov API v2. National Library of Medicine. Accessed March 29, 2026.
2. Page MJ, McKenzie JE, Bossuyt PM, et al. The PRISMA 2020 statement. BMJ. 2021;372:n71.
3. Borenstein M, Hedges LV, Higgins JPT, Rothstein HR. Introduction to Meta-Analysis. 2nd ed. Wiley; 2021.

AI Disclosure

This work represents a compiler-generated evidence micro-publication built from structured registry data and deterministic summary code. AI was used as a constrained coding and drafting assistant for interface generation, packaging, and prose refinement, not as an autonomous author. The analytical choices, interpretation, and final outputs were reviewed by the author, who takes responsibility for the content.