Mahmood Ahmad
Tahir Heart Institute
author@example.com

Protocol: CT.gov Design-Purpose Hiddenness

This protocol groups eligible older closed interventional ClinicalTrials.gov studies by sponsor-entered primary-purpose and allocation fields. Primary outputs compare two-year no-results rates, ghost-protocol rates, and full visibility across major purpose buckets, with a secondary allocation contrast and size-within-purpose view. The aim is to test whether design intent corresponds to different public visibility profiles rather than treating all interventional studies as one bucket. Because purpose and allocation are sponsor-entered labels, the project measures registry-design labeling rather than externally audited trial design.

Outside Notes

Type: protocol
Primary estimand: 2-year no-results rate across primary-purpose groups among eligible older CT.gov studies
App: CT.gov Design-Purpose Hiddenness dashboard
Code: https://github.com/mahmood726-cyber/ctgov-design-purpose-hiddenness
Date: 2026-03-29
Validation: FULL REGISTRY RUN

References

1. ClinicalTrials.gov API v2. National Library of Medicine. Accessed March 29, 2026.
2. Zarin DA, Tse T, Williams RJ, Carr S. Trial reporting in ClinicalTrials.gov. N Engl J Med. 2016;375(20):1998-2004.
3. DeVito NJ, Bacon S, Goldacre B. Compliance with legal requirement to report clinical trial results on ClinicalTrials.gov: a cohort study. Lancet. 2020;395(10221):361-369.

AI Disclosure

This work represents a compiler-generated evidence micro-publication built from structured registry data and deterministic summary code. AI was used as a constrained coding and drafting assistant for interface generation, packaging, and prose refinement, not as an autonomous author. The analytical choices, interpretation, and final outputs were reviewed by the author, who takes responsibility for the content.