Mahmood Ahmad
Tahir Heart Institute
author@example.com

Protocol: CT.gov Country Excess Watchlist

This protocol explodes named-country links inside eligible older closed interventional ClinicalTrials.gov studies and reuses the wave-eight study-mix adjustment to rank country-linked portfolios. Primary outputs compare adjusted no-results excess, adjusted ghost excess, black-box stock, overdue depth, and strict-core spillover across countries with at least 500 linked older studies. The aim is to move beyond raw national rates and ask which country-linked portfolios still remain worse than expected after visible study mix is held more constant. Because multinational studies are linked to more than one country, the outputs describe country-linked portfolios rather than mutually exclusive national totals.

Outside Notes

Type: protocol
Primary estimand: Adjusted excess no-results and ghost stock across country-linked study portfolios with at least 500 linked studies
App: CT.gov Country Excess Watchlist dashboard
Code: https://github.com/mahmood726-cyber/ctgov-country-excess-watchlist
Date: 2026-03-29
Validation: FULL REGISTRY RUN

References

1. ClinicalTrials.gov API v2. National Library of Medicine. Accessed March 29, 2026.
2. DeVito NJ, Bacon S, Goldacre B. Compliance with legal requirement to report clinical trial results on ClinicalTrials.gov: a cohort study. Lancet. 2020;395(10221):361-369.
3. Zarin DA, Tse T, Williams RJ, Carr S. Trial reporting in ClinicalTrials.gov. N Engl J Med. 2016;375(20):1998-2004.

AI Disclosure

This work represents a compiler-generated evidence micro-publication built from structured registry data and deterministic summary code. AI was used as a constrained coding and drafting assistant for interface generation, packaging, and prose refinement, not as an autonomous author. The analytical choices, interpretation, and final outputs were reviewed by the author, who takes responsibility for the content.