Mahmood Ahmad
Tahir Heart Institute
author@example.com

Protocol: CT.gov Country-Condition Hiddenness

This protocol explodes eligible older closed interventional ClinicalTrials.gov studies into named-country cells and then restricts the analysis to oncology, cardiovascular, and metabolic condition families. Primary outputs compare two-year no-results rates, ghost-protocol rates, and fully visible shares across condition-country cells with at least 400 eligible older studies. The aim is to test whether disease-family visibility depends on which national footprints are attached to the study record rather than on condition label alone. Because the cells use recorded study locations, the analysis measures country involvement rather than verified enrollment shares, sponsor domicile, or national legal exposure.

Outside Notes

Type: protocol
Primary estimand: 2-year no-results rate across selected country-by-condition cells among eligible older CT.gov studies
App: CT.gov Country-Condition Hiddenness dashboard
Code: https://github.com/mahmood726-cyber/ctgov-country-condition-hiddenness
Date: 2026-03-29
Validation: FULL REGISTRY RUN

References

1. ClinicalTrials.gov API v2. National Library of Medicine. Accessed March 29, 2026.
2. Zarin DA, Tse T, Williams RJ, Carr S. Trial reporting in ClinicalTrials.gov. N Engl J Med. 2016;375(20):1998-2004.
3. DeVito NJ, Bacon S, Goldacre B. Compliance with legal requirement to report clinical trial results on ClinicalTrials.gov: a cohort study. Lancet. 2020;395(10221):361-369.

AI Disclosure

This work represents a compiler-generated evidence micro-publication built from structured registry data and deterministic summary code. AI was used as a constrained coding and drafting assistant for interface generation, packaging, and prose refinement, not as an autonomous author. The analytical choices, interpretation, and final outputs were reviewed by the author, who takes responsibility for the content.