Mahmood Ahmad
Tahir Heart Institute
author@example.com

Protocol: CT.gov Condition Excess Watchlist

This protocol merges one condition-family label onto each eligible older closed interventional ClinicalTrials.gov study and reuses the wave-eight study-mix adjustment to rank therapeutic portfolios. Primary outputs compare adjusted no-results excess, adjusted ghost excess, black-box stock, visible-share rates, and strict-core spillover across condition families. The aim is to separate count-heavy disease backlogs from portfolios that are especially ghosted or black-boxed relative to expectation. Because condition families are keyword-derived, the outputs approximate therapeutic portfolios rather than formal disease ontologies.

Outside Notes

Type: protocol
Primary estimand: Adjusted excess no-results and ghost stock across CT.gov condition families
App: CT.gov Condition Excess Watchlist dashboard
Code: https://github.com/mahmood726-cyber/ctgov-condition-excess-watchlist
Date: 2026-03-29
Validation: FULL REGISTRY RUN

References

1. ClinicalTrials.gov API v2. National Library of Medicine. Accessed March 29, 2026.
2. DeVito NJ, Bacon S, Goldacre B. Compliance with legal requirement to report clinical trial results on ClinicalTrials.gov: a cohort study. Lancet. 2020;395(10221):361-369.
3. Zarin DA, Tse T, Williams RJ, Carr S. Trial reporting in ClinicalTrials.gov. N Engl J Med. 2016;375(20):1998-2004.

AI Disclosure

This work represents a compiler-generated evidence micro-publication built from structured registry data and deterministic summary code. AI was used as a constrained coding and drafting assistant for interface generation, packaging, and prose refinement, not as an autonomous author. The analytical choices, interpretation, and final outputs were reviewed by the author, who takes responsibility for the content.