Mahmood Ahmad
Tahir Heart Institute
author@example.com

Protocol: CT.gov Completion-Delay Debt

This protocol groups eligible older closed interventional ClinicalTrials.gov studies by the delay between study first submission and primary completion. Primary outputs compare two-year no-results rates, ghost-protocol rates, and full visibility across delay buckets, with a secondary contrast for treatment and unlabeled-purpose studies. The aim is to test whether shorter operational cycles also correspond to faster public reporting. Because submission and completion dates can be backfilled or revised, the delay measure is a registry-timing proxy rather than a validated operational duration audit.

Outside Notes

Type: protocol
Primary estimand: 2-year no-results rate across registration-to-completion delay buckets among eligible older CT.gov studies
App: CT.gov Completion-Delay Debt dashboard
Code: https://github.com/mahmood726-cyber/ctgov-completion-delay-debt
Date: 2026-03-29
Validation: FULL REGISTRY RUN

References

1. ClinicalTrials.gov API v2. National Library of Medicine. Accessed March 29, 2026.
2. Zarin DA, Tse T, Williams RJ, Carr S. Trial reporting in ClinicalTrials.gov. N Engl J Med. 2016;375(20):1998-2004.
3. DeVito NJ, Bacon S, Goldacre B. Compliance with legal requirement to report clinical trial results on ClinicalTrials.gov: a cohort study. Lancet. 2020;395(10221):361-369.

AI Disclosure

This work represents a compiler-generated evidence micro-publication built from structured registry data and deterministic summary code. AI was used as a constrained coding and drafting assistant for interface generation, packaging, and prose refinement, not as an autonomous author. The analytical choices, interpretation, and final outputs were reviewed by the author, who takes responsibility for the content.