Mahmood Ahmad
Tahir Heart Institute
author@example.com

Protocol: CT.gov Completion Cohort Debt

This protocol groups eligible older closed interventional CT.gov studies by primary completion year and broader completion eras. Primary outputs estimate two-year no-results rates, ghost-protocol rates, and the share with both posted results and linked publications visible. The goal is to show whether later eligible cohorts actually look cleaner once every included study has had at least two years to report. Interpretation remains descriptive because registry mix, backfilling, and link-maintenance practices can also move cohort-level estimates.

Outside Notes

Type: protocol
Primary estimand: 2-year no-results rate by primary completion cohort among eligible older closed interventional studies
App: CT.gov Completion Cohort Debt dashboard
Code: https://github.com/mahmood726-cyber/ctgov-completion-cohort-debt
Date: 2026-03-29
Validation: FULL REGISTRY RUN

References

1. ClinicalTrials.gov API v2. National Library of Medicine. Accessed March 29, 2026.
2. Page MJ, McKenzie JE, Bossuyt PM, et al. The PRISMA 2020 statement. BMJ. 2021;372:n71.
3. Borenstein M, Hedges LV, Higgins JPT, Rothstein HR. Introduction to Meta-Analysis. 2nd ed. Wiley; 2021.

AI Disclosure

This work represents a compiler-generated evidence micro-publication built from structured registry data and deterministic summary code. AI was used as a constrained coding and drafting assistant for interface generation, packaging, and prose refinement, not as an autonomous author. The analytical choices, interpretation, and final outputs were reviewed by the author, who takes responsibility for the content.