Mahmood Ahmad
Tahir Heart Institute
author@example.com

Protocol: CT.gov Actual-Discipline Repeaters

This protocol defines an actual-discipline gap as a closed older study missing any of the registry fields covering actual primary completion, actual completion, or actual enrollment. Primary outputs compare named-sponsor stock and rate, sponsor-class rates, and component counts across the three actual-field domains. The aim is to isolate registry discipline around realized study timing and realized sample size. Missing actual-field markers do not by themselves establish legal violations or deliberate concealment.

Outside Notes

Type: protocol
Primary estimand: Any actual-field gap stock and rate among named lead sponsors with at least 100 older studies
App: CT.gov Actual-Discipline Repeaters dashboard
Code: https://github.com/mahmood726-cyber/ctgov-actual-discipline-repeaters
Date: 2026-03-29
Validation: FULL REGISTRY RUN

References

1. ClinicalTrials.gov API v2. National Library of Medicine. Accessed March 29, 2026.
2. DeVito NJ, Bacon S, Goldacre B. Compliance with legal requirement to report clinical trial results on ClinicalTrials.gov: a cohort study. Lancet. 2020;395(10221):361-369.
3. Zarin DA, Tse T, Williams RJ, Carr S. Trial reporting in ClinicalTrials.gov. N Engl J Med. 2016;375(20):1998-2004.

AI Disclosure

This work represents a compiler-generated evidence micro-publication built from structured registry data and deterministic summary code. AI was used as a constrained coding and drafting assistant for interface generation, packaging, and prose refinement, not as an autonomous author. The analytical choices, interpretation, and final outputs were reviewed by the author, who takes responsibility for the content.